Esare

15.03.2018 1 Comments

Reference herein to any specific service included linked websites does not necessarily constitute or imply its endorsement, recommendation, or promotion by the European Audiovisual Observatory, or the European Commission. Neither the European Commission, nor the European Audiovisual Observatory nor any of the employees of the respective organisations, makes any warranty, express or implied, or assumes any legal liability or responsibility for the accuracy, completeness, or usefulness of any information, or represents that its use would not infringe privately owned rights. To this end, we engineered a synthetic promoter, the enhanced synaptic activity-responsive element E-SARE , that drives neuronal activity-dependent gene expression more potently than other existing immediate-early gene promoters. If errors are brought to our attention, we will try to address them.

Esare


In a significant number of cases the identification of the company providing on-demand audiovisual services, and hence of the country of establishment of the services, is based on rational assumptions by the expert and analysts feeding the database. Expression of a drug-inducible Cre recombinase downstream of E-SARE enabled imaging of neuronal populations that respond to monocular visual stimulation and tracking of their long-distance thalamocortical projections in living mice. The software of the database was developed in the framework of a contract with the DG Communication of the European Commission and owned by the European Union represented by the European Commission. Whilst the software of the database is property of the European Union, the European Audiovisual Observatory is the owner of its content, with the exception of elements provided by third parties, in particular Lyngemark Satellite providing information on the line-up of satellite channels and Bureau Van Dijk providing information on the addresses of companies. In particular, the criteria used to include audiovisual services television, on-demand audiovisual services in the database are not completely similar to those defined by the European Directive on Audiovisual Services or by the transposition of this Directive in the national laws of Member States. The data collection process has benefited from the help of the European Platform of Regulatory Authorities. Neither the European Commission, nor the European Audiovisual Observatory nor any of the employees of the respective organisations, makes any warranty, express or implied, or assumes any legal liability or responsibility for the accuracy, completeness, or usefulness of any information, or represents that its use would not infringe privately owned rights. To this end, we engineered a synthetic promoter, the enhanced synaptic activity-responsive element E-SARE , that drives neuronal activity-dependent gene expression more potently than other existing immediate-early gene promoters. The fact that a television service or an on-demand audiovisual service is included in the database does not represent a position from the Observatory, from the European Commission or from any regulatory authority regarding its legal situation. This activity-dependent promoter can expand the repertoire of genetic approaches for high-resolution anatomical and functional analysis of neural circuits. Targeted cell-attached recordings and calcium imaging of neurons in sensory cortices revealed that E-SARE reporter expression correlates with sensory-evoked neuronal activity at the single-cell level and is highly specific to the type of stimuli presented to the animals. If errors are brought to our attention, we will try to address them. Epub Jul While every care has been taken to ensure accuracy, no guarantee is given that the material is free from error or omission. Functional labeling of neurons and their projections using the synthetic activity-dependent promoter E-SARE. The views and opinions of authors expressed herein do not necessarily state or reflect those of the European Commission or the European Audiovisual Observatory or the Council of Europe. In particular, an important number of on-demand audiovisual services accessible through distribution platforms do not provide clear identification of the company providing services. Reference herein to any specific service included linked websites does not necessarily constitute or imply its endorsement, recommendation, or promotion by the European Audiovisual Observatory, or the European Commission. Identifying the neuronal ensembles that respond to specific stimuli and mapping their projection patterns in living animals are fundamental challenges in neuroscience. Erratum in Nat Methods. The data collection process of information on the European television and on-demand audiovisual markets by the European Audiovisual Observatory is partly made possible in the context of a framework contract with the DG Communication of the European Commission and specific contracts with this DG for television and DG for Communications Networks Content and Technology for on-demand audiovisual services. Our goal is to keep this information timely and accurate.

Esare


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